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An enzyme-linked receptor, also known as a catalytic receptor, is a transmembrane receptor, where the binding of an extracellular ligand causes enzymatic activity on the intracellular side. Hence a catalytic receptor is an integral membrane protein possessing both enzymatic catalytic and receptor functions. They have two important domains, an extra-cellular ligand binding domain and an intracellular domain, which has a Catalytic function; and a transmembrane helix. The signaling molecule binds to the receptor outside of the cell and causes a conformational change on the Catalytic function located on the receptor inside of the cell. Examples of the enzymatic activity include: * Receptor tyrosine kinase, as in fibroblast growth factor receptor. Most enzyme-linked receptors are of this type.〔(lecture10 )〕 * Serine/threonine-specific protein kinase, as in bone morphogenetic protein * Guanylate cyclase, as in atrial natriuretic factor receptor == Types == The following is a list of the five major families of catalytic receptors: 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Enzyme-linked receptor」の詳細全文を読む スポンサード リンク
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